Introduction
Few travel experiences capture the spirit of freedom quite like a road trip. Windows down, playlists on, and endless scenery unfolding mile by mile—road trips are the ultimate way to savor America’s vast and varied landscapes. Whether you crave coastal drives, mountain passes, or historic byways, the U.S. offers some of the world’s most iconic routes.
And the best part? You don’t need to start the drive from your hometown. With Door2Door Flights, you can fly affordably into a gateway city and hit the open road from there. In this guide, we’ll explore ten of the best road trip routes in the U.S. before summer ends, with practical tips on where to fly, what to see, and how to make the most of the adventure.
Why Road Trips Define the American Summer
Generations of travelers have hit the road each summer to discover the U.S. by car. A 2025 travel survey shows road trips remain one of the top vacation choices, blending affordability with adventure. Unlike tours, road trips let you set the pace, explore hidden gems, and customize your route. By pairing smart flight planning with flexible driving itineraries, you can maximize both time and budget.
Epic U.S. Road Trip Destinations
1. Pacific Coast Highway (California)
Stretching from San Francisco to Los Angeles, the Pacific Coast Highway is a bucket-list drive featuring rugged cliffs, Big Sur’s breathtaking coastline, and charming seaside towns like Carmel-by-the-Sea. Fly into San Francisco or Los Angeles to start the journey. Don’t miss Hearst Castle or the iconic Bixby Bridge.
2. Route 66 (Chicago to Santa Monica)
Known as the Mother Road, Route 66 offers Americana at its finest—retro diners, quirky roadside attractions, and stretches of desert highway. Start your trip with flights from Chicago, where the route begins, and head west through eight states until you reach the Pacific.
3. Blue Ridge Parkway (Virginia to North Carolina)
Winding through the Appalachian Mountains, the Blue Ridge Parkway is one of the most scenic drives in the East. Fly into Charlotte and enjoy panoramic views, hiking trails, and charming Southern towns. This route is especially stunning in late summer and early fall.
4. Florida Keys Overseas Highway
Connecting Miami to Key West, the Overseas Highway feels like driving across the ocean. With turquoise waters on both sides, this route is ideal for those craving sunshine and relaxation. Book flights from Miami and spend a few days snorkeling, diving, and exploring island life.
5. The Great River Road (Minnesota to Louisiana)
Following the Mississippi River, the Great River Road spans 10 states and 3,000 miles. The southern leg—from Memphis to New Orleans—offers the best blend of culture, music, and cuisine. Start with flights from New Orleans and work your way north along historic towns and river views.
6. Southwest National Parks Loop (Utah, Arizona & Nevada)
For those who love red rock landscapes and desert adventures, the Southwest National Parks Loop delivers Zion, Bryce Canyon, the Grand Canyon, and more. Fly into Las Vegas for easy access to the loop. Pack your hiking boots—you’ll need them.
7. New England Fall Foliage Drive
New England’s country roads, covered bridges, and brilliant autumn leaves make it a dreamy late-summer-to-fall road trip. Start with flights from Boston and drive north through Vermont, New Hampshire, and Maine. Highlights include apple orchards, mountain hikes, and cozy inns.
8. Alaska’s Seward Highway
For untamed wilderness, the Seward Highway outside Anchorage is unbeatable. Expect glaciers, fjords, and dramatic mountain peaks. Begin with flights from Anchorage and explore destinations like Kenai Fjords National Park or Turnagain Arm, where beluga whales can sometimes be spotted.
9. Texas Hill Country Wine Trail
If you’re looking for a mix of culture and relaxation, the Texas Hill Country is dotted with wineries, small towns, and rolling landscapes. Fly into Austin and enjoy local BBQ, music, and scenic backroads between Fredericksburg and Wimberley.
10. Going-to-the-Sun Road (Montana)
Cutting through Glacier National Park, Going-to-the-Sun Road offers alpine lakes, rugged peaks, and wildlife like mountain goats and bears. While flights into Denver can serve as a gateway, regional travelers often connect to Kalispell for easier access.
How to Plan the Perfect Road Trip
- Choose your route: Decide which region matches your travel style.
- Book flights into a starting city: Use Door2Door Flights for affordable fares.
- Rent a car or camper: Flexible vehicles give you freedom.
- Plan stops wisely: Mix big highlights with hidden gems.
- Budget ahead: Road trips are flexible, but costs can add up without planning.
Benefits of Road Trips
- Explore at your own pace
- Cost-effective compared to multi-stop flights
- Access to remote destinations not served by airports
- Opportunity to combine flights + car rentals for the best of both worlds
Common Mistakes to Avoid
- Overpacking your schedule: Distances are longer than they look.
- Not booking flights early enough: Even affordable fares can rise in peak summer.
- Ignoring weather conditions: Mountain passes and coastal roads can be affected by storms.
- Forgetting to budget gas & food stops: These add up.
Conclusion
From coastal drives to mountain highways, America’s roads offer a front-row seat to its most spectacular landscapes. Pairing smart flight planning with a well-mapped itinerary makes it easier than ever to embark on these adventures. So whether you’re flying into Los Angeles, Chicago, or Miami, let Door2Door Flights take you to the gateway of your next great r
